A total of 163 patients with a cardiac one- or two-chamber pacemaker were included in this prospective, multicentre observational study. Weipert KF, Bogossian H, Conzen P, Frommeyer G, Gemein C, Helmig I, Chasan R, Eckardt L, Seyfarth M, Lemke B, Zarse M, Hamm CW, Schmitt J, Erkapic D. Clin Res Cardiol. Herzschrittmacherther Elektrophysiol 26(4):374398 CrossRef, Zurck zum Zitat Rautaharju PM, Surawicz B, Gettes LS, Bailey JJ, Childers R et al (2009) AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology. EP - 1039 HHS Vulnerability Disclosure, Help Twelve-lead ECG recordings were obtained during both intrinsic rhythm and RV pacing with induced LBBB. The Bogossian formula is a reliable tool for QTc interval evaluation in pacemaker patients with LBBB due to apical or non-apical RV pacing and preserved left ventricular function. [email protected]; Mrkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Ldenscheid, Ldenscheid, Germany. Reply: QT interval measurements in patients with left bundle branch block. Deine E-Mail-Adresse wird nicht verffentlicht. PMC Epub 2014 Aug 19. eCollection 2020 Oct. Ann Noninvasive Electrocardiol. Up to now, there is no clear, View 5 excerpts, references background and methods, Journal of Interventional Cardiac Electrophysiology. QT-Zeit und QRS-Breite knnen (natrlich nach visueller berprfung ) dem EKG-Auswertealgorithmus entnommen oder per EKG-Lineal gemessen werden. Please confirm that you would like to log out of Medscape. 2017 Apr;40(4):409-416 8600 Rockville Pike In the case of pacemaker stimulation, the Bogossian formula was additionally applied (31). Unfortunately the Bazett correction overcorrects with heart rates >110 bpm and undercorrects with heart rates < 60 bpm. The newest formula to evaluate QT interval in the presence of LBBB suggests: modified QT during LBBB = measured QT interval minus 50% of LBBB duration. Bookshelf Careers. 2020 Sep;43(9):957-962. doi: 10.1002/clc.23389. eCollection 2020 Oct. QTc interval evaluation in patients with right bundle branch block or bifascicular blocks. Epub 2017 Mar 3. Cutting off half of QRS duration can cause overcorrection ofQT interval in left bundle branch block. In 2014, a new formula for the evaluation of. Ann Noninvasive Electrocardiol. Bethesda, MD 20894, Web Policies An approach to the ECG in this context, and a step-by-step guide to manually measuring and correcting the QT interval, and an approach to management in common hospital-based clinical scenarios are presented. Herzschrittmacherther Elektrophysiol 26(4):374398, Rautaharju PM, Surawicz B, Gettes LS, Bailey JJ, Childers R et al (2009) AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology. 2020 Sep;43(9):957-962. doi: 10.1002/clc.23389. INTERNET EXPLORER WIRD NICHT MEHR UNTERSTZT, verfasst von: Provided by the Springer Nature SharedIt content-sharing initiative, Over 10 million scientific documents at your fingertips, Not logged in 8600 Rockville Pike However, an overestimation of 30 ms should be included in the calculation. The JTc is a simple measurement that is a significant independent predictor of incident CHD events in men with wide QRS complex, and a more valid way to assess ventricular repolarization. Latest evidence on COVID-19 from PubMed, WHO, CDC. 12 PDF Assessment of QT and JT Intervals in Patients With Left Bundle Branch Block P. Tabatabaei, Ala Keikhavani, +6 authors A. Alizadeh SP - 1033 However, an overestimation of 30 ms. Pacing and clinical electrophysiology : PACE, The presence of left bundle branch block (LBBB) due to right ventricular pacing represents a particular challenge in properly measuring the QTc interval. In the non-apical group these values were 430 34 ms in paced and 416 32 ms in intrinsic rhythm. Die Bogossian-Formel ist eine alltagstaugliche Methode, die mutmalich wahre Dauer der Repolarisation im EKG mit verbreiterten Kammerkomplexen zu ermitteln. ECG parameters, such as QTcH, TP and TP/QT do not helpful predicting Troponin I elevations in patients on anthracycline-based chemotherapy, and further studies based on hard endpoints, for example, clinical systolic dysfunction occurring at one year, would give better information on their utility. PubMedGoogle Scholar. Please enable it to take advantage of the complete set of features! The .gov means its official. D. Erkapic. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. Before This 'Bogossian' formula was reported to be a reliable tool for QT interval estimation in patients with heart failure and right ventricular pacing [ 9 ]. A more precise formula was developed and described by Rautaharju et al. Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block. Herzschrittmacherther Elektrophysiol. Unauthorized use of these marks is strictly prohibited. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Diagnosis of myocardial infarction and ischemia in the setting of bundle branch block and cardiac pacing. HHS Vulnerability Disclosure, Help KW - QT formula PY - 2018/5/13/pubmed 2014 Jan;15(1):25-36. doi: 10.1714/1394.15516. 2017 Jul;22(4):e12475. FOIA Background: The site is secure. Conclusion In combination with the Hodge formula, the Boggosian formula delivered the best results in comparing the true QTc interval in narrow QRS with the QTmc interval in the presence of a bifascicular block. Inclusion criteria were: no permanent right ventricular stimulation, an intrinsic QRS interval of <120 ms, and reduced left ventricular function. Disclaimer. AU - Zarse,M, Eighty-three patients (789years; male. Here we demonstrate the applicability of the "Bogossian formula" in pacemaker patients with LBBB due to apical or nonapical right ventricular (RV) pacing and preserved left ventricular function. @article{Bogossian2017ANE, title={A new experimentally validated formula to calculate the QT interval in the presence of left bundle branch block holds true in the clinical setting}, author={Harilaos Bogossian and Gerrit Frommeyer and Ilias Ninios and Eleni Pechlivanidou and Fuad Hasan and Quy Suu Nguyen and Dejan Miji{\'c} and Axel Kloppe and . Frommeyer G, Bogossian H, Pechlivanidou E, Conzen P, Gemein C, Weipert K, Helmig I, Chasan R, Johnson V, Eckardt L, Hamm CW, Seyfarth M, Lemke B, Zarse M, Schmitt J, Erkapic D. Pacing Clin Electrophysiol. The Bogossian formula is a reliable tool for QTc interval evaluation in pacemaker patients with LBBB due to apical or non-apical RV pacing. Introduction 2016. 2020 Sep 19;30:100636. doi: 10.1016/j.ijcha.2020.100636. haben 1973 einfach bei LSB QT-60 ms bzw. National Library of Medicine 2020 Sep 19;30:100636. doi: 10.1016/j.ijcha.2020.100636. 2021 Sep-Oct;62(5):501-510. doi: 10.1016/j.jaclp.2021.02.003. If you log out, you will be required to enter your username and password the next time you visit. Heart & Vasculature, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. A practice formula to eliminate the effect of depolarization changes on QT interval in patients with R BBB is developed and allows a rapid and practical method for QT correction in RBBB in clinical practice. sharing sensitive information, make sure youre on a federal 2016 in press Bogossian H, Frommeyer G, Ninios I, Hasan EP F, et al. Eighty-three patients (78 9 years; male n = 83) with apical and eighty patients (71 13 years; male n = 80) with non-apical RV pacing were included in this study. FOIA Heart Rhythm 5(7):10151018, Nielsen JB, Graff C, Rasmussen PV, Pietersen A, Lind B et al (2014) Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population. Weipert, K F., et al. The mean left ventricular ejection fraction was 40 13%. SpringerMedizin.de Mein Fachwissen. official website and that any information you provide is encrypted * Article titles in AMA citation format should be in sentence-case. KW - Left bundle branch block Department of Cardiology and Angiology, Medical Clinic I, University Clinic of Gieen, Gieen, Germany. In the non-apical group these values were 43034ms in paced and 41632ms in intrinsic rhythm. The presence of left bundle branch block (LBBB) represents a particular challenge in properly measuring the QT interval. Unfortunately the Bazett correction overcorrects with heart rates >110 bpm and undercorrects with heart rates < 60 bpm. Tex Heart Inst J. Texas Heart Inst J 33(1):38, Zurck zum Zitat Inoue K, Okayama H, Nishimura K, Saito M, Yoshii T et al (2011) Right ventricular septal pacing preserves global left ventricular longitudinal function in comparison with apical pacing: analysis of speckle tracking echocardiography. A total of 163 patients with a cardiac one- or two-chamber pacemaker were included in this prospective, multicentre observational study. CONCLUSION: The Bogossian formula is a reliable tool for QTc interval evaluation in pacemaker patients with LBBB due to apical or non-apical RV pacing. AU - Schmitt,J, By clicking accept or continuing to use the site, you agree to the terms outlined in our. Bethesda, MD 20894, Web Policies 2017 Apr;40(4):409-416. doi: 10.1111/pace.13027. 2017 Jul;22(4):e12475. Fr die nach Bogossian modifizierte QT sollte dies mglichst mit der Hodges-Formel (nicht Bazett oder Fridericia) erfolgen. AU - Helmig,I, Pacemaker and AQUA Institute for Applied Quality Improvement and Research in Health Care GmbH workgroup. the correction formula used to correct the QT-interval for heart rate, age and/or sex, although age and sex are known modulating factors of the QTc-interval. Am J Cardiol 55(11):13321338, Article - 193.70.22.229. A beautiful, free online scientific calculator with advanced features for evaluating percentages, fractions, exponential functions, logarithms, trigonometry, statistics, and more. The novel Bogossian formula seems to be a reliable tool for QTc interval evaluation in patients with heart failure and right ventricular pacing. 2004), Deine E-Mail-Adresse wird nicht verffentlicht. and covers all kinds of ventricular conduction defects (LBBB, RBBB and intraventricular delay) and the complete heart-rate spectrum (Table 1 ). 3.Heart Rate? JT interval; Left bundle branch block; Long QT; Pacemaker; QT formula; QT interval. However, an overestimation of 30 ms should be included in the calculation. Epub 2017 Jun 7. The authors declare that they have no conflicts of interest. 2013 Jun;10(6):330-7 The authors have no conflicts of interests to disclose. Pacing Clin Electrophysiol 37(6):724730. QTb = gemessene QT-Zeit Lewis AJM, Foley P, Whinnett Z, Keene D, Chandrasekaran B. J Am Heart Assoc. doi: 10.1111/anec.12475. Abb.). A new experimentally validated formula to calculate the QT interval in the presence of left bundle branch block holds true in the clinical setting - Bogossian - 2017 - Annals of Noninvasive Electrocardiology - Wiley Online Library ORIGINAL ARTICLE Free to Read IS - 11 A comparison of commonly used QT correction formulae: the effect of heart rate on the QTc of normal ECGs. This website also contains material copyrighted by 3rd parties. sharing sensitive information, make sure youre on a federal Assessment of left ventricular dyssynchrony in pacing-induced left bundle branch block compared with intrinsic left bundle branch block. Dr. Saige's primary research is focused on heart valve diseases and transesophageal echocardiography. The Bogossian formula showed a significant deviation from the actual QTc interval with both the Bazett and the Fridericia formulas. Learn more about Institutional subscriptions, Woosley RL, Romero K (2013) Assessing cardiovascular drug safety for clinical decision-making. However, an overestimation of 30 ms should be included in the calculation. Weipert KF, Bogossian H, Conzen P, et al. 2016 in press, Markewitz A (2015) Annual report 2013 of the German Cardiac Pacemaker And Defibrillator RegisterPart 2: implantable cardioverter-defibrillators. Federal government websites often end in .gov or .mil. CAS 2018 Dec;53(3):347-355. doi: 10.1007/s10840-018-0449-5. -. International journal of cardiology. 2018) und anderen Blockbildern (Bogossian et al. Unfortunately the Bazett correction overcorrects with heart rates >110 bpm and undercorrects with heart rates <60 bpm. KW - Pacemaker SN - 1861-0692 Incidence and outcomes of long QTc in acute medical admissions. An official website of the United States government. QTc evaluation in patients with bundle branch block. The QTc interval was overestimated by QTc of 25 21 ms (mean deviation 5.7%) when using the Bogossian formula. A New Formula for Estimating the True QT Interval in Left Bundle Branch Block. The .gov means its official. QT interval prolongation is associated with a risk of polymorphic ventricular tachycardia and torsades de pointes, and there was no significant difference between the QTc interval in AF and SR when assessed by Fredericias formula. The QTmc interval was calculated with the Bazett formula, and this was compared with the QTc interval during intrinsic rhythm. (AHA/ACCF/HRS Recommendations 2009 und Rautaharju PM et al. All measurements were performed by an experienced electrophysiologist and a trainee who worked independently and in a blinded manner. : A new experimentally validated formula to calculate the QT-interval in the presence of left bundle branch block holds true in the clinical setting. KW - JT interval Circ J 75(7):16091615, Pang BJ, Kumar S, Tacey MA, Mond HG (2014) Capturing the His-Purkinje system is not possible from conventional right ventricular apical and nonapical pacing sites. Epub 2018 Sep 17. N Engl J Med 348(19):18661874, Rautaharju PM, Zhang ZM, Prineas R, Heiss G (2004) Assessment of prolonged QT and JT intervals in ventricular conduction defects. Would you like email updates of new search results? Unable to load your collection due to an error, Unable to load your delegates due to an error, Simplified formula for determination of the. Google Scholar, Schneider JF, Thomas HE Jr, McNamara PM, Kannel WB (1985) Clinical-electrocardiographic correlates of newly acquired left bundle branch block: the Framingham Study. Bogossian H, Frommeyer G, Ninios I, Hasan F, Nguyen QS, Karosiene Z, Mijic D, Kloppe A, Suleiman H, Bandorski D, Seyfarth M, Lemke B, Eckardt L, Zarse M. Heart Rhythm. QTc evaluation in patients with bundle branch block. QTc-70 ms und bei RSB QT-30 ms bzw. Would you like email updates of new search results? We thank Inga Bayh and Prof. Dr. Frank Krummenauer (Institute for Medical Biometry and Epidemiology, School of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany) for statistical advice. Bogossian H, Linz D, Heijman J, Bimpong-Buta NY, Bandorski D, Frommeyer G, Erkapic D, Seyfarth M, Zarse M, Crijns HJ. The evaluation of the QT interval in the presence of left bundle branch block (LBBB) is associated with the challenge to discriminate native QT interval from the prolongation due to the increase in QRS duration. Reply: QT interval measurements in patients with left bundle branch block. The https:// ensures that you are connecting to the See this image and copyright information in PMC. 20002023 Unbound Medicine, Inc. All rights reserved, TY - JOUR 2019 Mar 19;8(6):e010972. Heart Rhythm. Federal government websites often end in .gov or .mil. 2017 Apr;40(4):409-416. doi: 10.1111/pace.13027. Accessibility Bogossian H, Linz D, Heijman J, Bimpong-Buta NY, Bandorski D, Frommeyer G, Erkapic D, Seyfarth M, Zarse M, Crijns HJ. Clipboard, Search History, and several other advanced features are temporarily unavailable. Here we demonstrate the applicability of the "Bogossian formula" in pacemaker patients with LBBB due to apical or nonapical right ventricular (RV) pacing and preserved left ventricular function. An official website of the United States government. Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block Clin Res Cardiol. The Bogossian formula is a reliable tool for QTc interval evaluation in pacemaker patients with LBBB due to apical or non-apical RV pacing. Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert ganz bequem per eMail. In the apical group the QTmc was determined to be 44439ms in paced rhythm and the QTc interval 41336ms in intrinsic rhythm. K. F. Weipert, H. Bogossian, P. Conzen, G. Frommeyer, C. Gemein, I. Helmig, R. Chasan, L. Eckardt, M. Seyfarth, B. Lemke, M. Zarse, C. W. Hamm, J. Schmitt, D. Erkapic, Erschienen in: Pacing Clin Electrophysiol 40(4):409416 CrossRef, Zurck zum Zitat Frommeyer G, Milberg P, Witte P, Stypmann J, Koopmann M et al (2011) A new mechanism preventing proarrhythmia in chronic heart failure: rapid phase-III repolarization explains the low proarrhythmic potential of amiodarone in contrast to sotalol in a model of pacing-induced heart failure. Heart Rhythm 11(12):22732277 CrossRef, Zurck zum Zitat Bogossian H, Frommeyer G, Ninios I, Hasan EP F, et al. New formula for evaluation of the QT interval in patients with left bundle branch block. An improved method for adjusting the QT interval for heart rate (the Framingham Heart Study). PMC After LBBB correction using the reported Bogossian formula, the QTc interval was evaluated with Bazett's formula. AU - Bogossian,H, 2.QT Interval? HHS Vulnerability Disclosure, Help : A new experimentally validated formula to calculate the QT-interval in the presence of left bundle branch block holds true in the clinical setting. Epub 2014 Aug 19. Eur J Heart Fail 13(10):10601069, Frommeyer G, Rajamani S, Grundmann F, Stypmann J, Osada N et al (2012) New insights into the beneficial electrophysiologic profile of ranolazine in heart failure: prevention of ventricular fibrillation with increased postrepolarization refractoriness and without drug-induced proarrhythmia. [email protected]. Subsequently, rate-correction formula should be applied as usual. At extremes of Heart Rate the Hodges correction may perform better than Bazett correction. New formula for evaluation of the QT interval in patients with left bundle branch block. Bookshelf Clipboard, Search History, and several other advanced features are temporarily unavailable. In the apical group the QTmc was determined to be 444 39 ms in paced rhythm and the QTc interval 413 36 ms in intrinsic rhythm. Would you like email updates of new search results? Disclaimer. New formula for defining "normal" and "prolonged" QT in patients with bundle branch block. Pacemaker and AQUA Institute for Applied Quality Improvement and Research in Health Care GmbH workgroup. Epub 2014 Aug 19. e.g. JO - Clin Res Cardiol The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Completing the square method is a technique for find the solutions of a quadratic equation of the form ax^2 + bx + c = 0. Genau wie die QT-Zeit bei normalen QRS muss auch die so modifizierte QT-Zeit frequenzkorrigiert werden, sofern die Frequenz nennenswert von 60 min-1 abweicht. Feasibility of RA-LV pacing in patients with symptomatic left bundle branch block: a pilot study. 2014 Dec;11(12):2273-7 2018 Nov;72(11):e13250. The newest formula to evaluate QT interval in the presence of LBBB suggests: modified QT during LBBB = measured QT interval minus 50% of LBBB duration. Cardiology 130(4):207210 CrossRef, Zurck zum Zitat Frommeyer G, Bogossian H, Pechlivanidou E, Conzen P, Gemein C et al (2017) Applicability of a novel formula (Bogossian formula) for evaluation of the QT-interval in heart failure and left bundle branch block due to right ventricular pacing. Novel approach to discriminate left bundle branch block from nonspecific intraventricular conduction delay using pacing-induced functional left bundle branch block. Epub 2018 May 11. Previously, he was a researcher for the Framingham Heart Study in Boston, Massachusetts. 2014 Dec;11(12):2273-7. doi: 10.1016/j.hrthm.2014.08.026. The QT interval measured during LBBB was corrected using the Bogossian formula to obtain the modified QT (QTm). The QTmc interval was calculated with the Bazett formula, and this was compared with the QTc interval during intrinsic rhythm. This information should not be used for the diagnosis or treatment of any health problem or disease. Bogossian H, Linz D, Heijman J, Bimpong-Buta NY, Bandorski D, Frommeyer G, Erkapic D, Seyfarth M, Zarse M, Crijns HJ. Department of Cardiology, Diakonie Jung-Stilling Hospital, Wichernstrasse 40, 57074, Siegen, Germany. Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block. Applicability of a Novel Formula (Bogossian formula) for Evaluation of the QT-Interval in Heart Failure and Left Bundle Branch Block Due to Right Ventricular Pacing Applicability of a Novel Formula (Bogossian formula) for Evaluation of the QT-Interval in Heart Failure and Left Bundle Branch Block Due to Right Ventricular Pacing QTc evaluation in patients with bundle branch block. (Erkapic D et al. Bethesda, MD 20894, Web Policies The most commonly used QT correction is that of Bazett which was proposed in 1920. Int J Cardiol Heart Vasc. Methods: The QTmc interval was calculated with the Bazett formula, and this was compared with the QTc interval during intrinsic rhythm. Epub 2018 Sep 19. In addition to the standard electrical parameter QTc, we assessed markers for regional electrical. 2018 Nov;107(11):1033-1039. doi: 10.1007/s00392-018-1275-6. Keywords: The ECG pattern of high-grade LAD stenosis has proven to be an important marker ofhigh-risk patients with chest pain and may also be seen in patients with a right ventricular pacemaker on resumption of native QRS conduction. New formula for evaluation of the QT interval in patients with left bundle branch block. The QT-interval you use to enter in the calculator should preferably be determined from the average of 3 consecutive beats. A total of 163 patients with a cardiac one- or two-chamber pacemaker were included in this prospective, multicentre observational study. In the non-apical group these values were 430 34 ms in paced and 416 32 ms in intrinsic rhythm. QTc-40 ms verwandt. 2015 Dec;26(4):374-98 Pacemaker and AQUA Institute for Applied Quality Improvement and Research in Health Care GmbH workgroup. eCollection 2020 Oct. Wang B, Zhang LI, Cong P, Chu H, Liu Y, Liu J, Surkis W, Xia Y. J Cardiovasc Electrophysiol. 2020). Int J Cardiol Heart Vasc. PY - 2017/12/16/received 2020 Sep;43(9):957-962. doi: 10.1002/clc.23389. JT interval; QT formula; QT interval; QT prolongation; heart failure; left bundle brunch block; long QT. Conclusion In combination with the Hodge formula, the. The Bogossian formula showed a significant deviation from the actual QTc interval with both the Bazett and the Fridericia formulas. The QT interval of the electrocardiogram is prolonged in right and left bundle-branch block, which is probably due to the conduction defect and delayed depolarization (and thus repolarization) of the heart. PY - 2018/05/07/accepted Unauthorized use of these marks is strictly prohibited. FOIA Heart Rhythm 5(7):10151018 CrossRef, Zurck zum Zitat Nielsen JB, Graff C, Rasmussen PV, Pietersen A, Lind B et al (2014) Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population. The QT interval measured during LBBB was corrected using the Bogossian formula to obtain the modified QT (QTm). MeSH An official website of the United States government. -, Herzschrittmacherther Elektrophysiol. Epub 2018 Jan 31. In 2014, a new formula for the evaluation of QT interval in patients with LBBB was reported. New formula for evaluation of the QT interval in patients with left bundle branch block. 26(4):399423 CrossRef, Zurck zum Zitat Markewitz A (2015) Annual report 2013 of the German Cardiac Pacemaker and Defibrillator Register, part 1Pacemaker. Clipboard, Search History, and several other advanced features are temporarily unavailable. This site needs JavaScript to work properly. Seeing through the maze of complete left bundle branch block. Calculate the corrected QT interval Questions 1.QT Correction? Epub 2021 Feb 13. AU - Hamm,C W, Clipboard, Search History, and several other advanced features are temporarily unavailable. All measurements were performed by an experienced electrophysiologist and a trainee who worked independently and in a blinded manner. AU - Erkapic,D, Comparison of left ventricular torsion and strain with biventricular pacing in patients with underlying right bundle branch block versus those with left bundle branch block. Bei LSB, RSB und rechtsventrikulrer Schrittmacher-Stimulation sind die sonst blichen Grenzwerte fr die QT-Zeit deshalb nicht geeignet, die Arrhythmiegefhrdung betroffener Patienten abzuschtzen. Sagie A, Larson MG, Goldberg RJ, Bengston JR, Levy D. Luo S, Michler K, Johnton P, Macfarlane PW. 2020 QxMD Software Inc., all rights reserved. Weipert, K.F., Bogossian, H., Conzen, P. et al. Causes of prolonged QT include drugs (antiarrhythmics, psychotropics, antihistamines, antibiotics and antifungals), electrolyte abnormalities (hypokalemia, hypomagnesemia, hypocalcemia), myocardial pathology (ischemia, myocarditis, post-pacing), hypothyroidism, intracranial pathology and congenital casues among others. official website and that any information you provide is encrypted Bethesda, MD 20894, Web Policies Tablot et al. N2 - BACKGROUND: The presence of left bundle branch block (LBBB) represents a particular challenge in properly measuring the QT interval. Scholz EP, Fischer P, Lugenbiel P, Xynogalos P, Schweizer PA, Scherer D, Thomas D, Katus HA, Zitron E. J Interv Card Electrophysiol. 2016 in press, Zurck zum Zitat Markewitz A (2015) Annual report 2013 of the German Cardiac Pacemaker And Defibrillator RegisterPart 2: implantable cardioverter-defibrillators. 2018 May-Jun;51(3):481-486. doi: 10.1016/j.jelectrocard.2017.12.039. N Engl J Med 348(19):18661874 CrossRef, Zurck zum Zitat Rautaharju PM, Zhang ZM, Prineas R, Heiss G (2004) Assessment of prolonged QT and JT intervals in ventricular conduction defects. Background: 2017 Jun;28(6):684-689. doi: 10.1111/jce.13203. The QT interval measured during LBBB was corrected using the Bogossian formula to obtain the "modified QT" (QTm). government site. The Bogossian formula showed a significant deviation from the actual QTc interval with both the Bazett and the Fridericia formulas. Eur J Heart Fail 13(10):10601069 CrossRef, Zurck zum Zitat Frommeyer G, Rajamani S, Grundmann F, Stypmann J, Osada N et al (2012) New insights into the beneficial electrophysiologic profile of ranolazine in heart failure: prevention of ventricular fibrillation with increased postrepolarization refractoriness and without drug-induced proarrhythmia.